Yakuchinone A

CAS No. 78954-23-1

Yakuchinone A( Yakuchinone-A )

Catalog No. M24785 CAS No. 78954-23-1

Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 222 In Stock
25MG 447 In Stock
50MG 651 In Stock
100MG 888 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Yakuchinone A
  • Note
    Research use only, not for human use.
  • Brief Description
    Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro.
  • Description
    Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro. Yakuchinone A inhibits the expression of cyclooxygenase-2 and of inducible nitric oxide synthase (iNOS).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Female C57BL/6 mice Dosage:50 mg/kg Administration:i.p., daily, 14 days Result:Showed a significant EAE score reduction from Day 9 to Day 15 after EAE onset.
  • Synonyms
    Yakuchinone-A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    78954-23-1
  • Formula Weight
    312.41
  • Molecular Formula
    C20H24O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(CCCCC1=CC=CC=C1)CCC2=CC=C(O)C(OC)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang Q, Cui C, Chen CQ, Hu XL, Liu YH, Fan YH, Meng WH, Zhao QC. Anti-proliferative and pro-apoptotic activities of Alpinia oxyphylla on HepG2 cells through ROS-mediated signaling pathway. J Ethnopharmacol. 2015 Jul 1;169:99-108. doi: 10.1016/j.jep.2015.03.073. Epub 2015 Apr 16. PubMed PMID: 25891473.
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